Cyclobenzaprine Use During Pregnancy

Pregnant patients may experience illnesses or injuries that require procedural sedation. When managing a pregnant patient who requires procedural sedation, providers must be cognizant of both the physiologic changes that may affect sedation as well as the safety of the medications used. (Table 5) Consultation with a provider with experience in obstetric anesthesia is prudent for patients in late pregnancy who require procedural sedation, particularly in more complicated cases. Cyclobenzaprine (Flexeril) is commonly used to relieve muscle sprain, and healthcare providers prescribe this drug for short-term usage. However, if you are a lactating woman, you might be concerned about the safety of taking Flexeril when breastfeeding. Flexeril has been classified as Pregnancy Category B by the Food and Drug Administration 1.

• It works by acting in the brain and nervous system to allow the muscles to relax.
• Pregnant women, and people with a history of depression or substance abuse problems should not take muscle relaxants.
• As per information available through research, there is no evidence that suggests Cyclobenzaprine causes miscarriage during pregnancy.
• One study demonstrated that 1% of pregnant near-term women  admitted to non-medical use of a prescription opioid analgesic within the past 30 days.
• Your condition will not improve any faster, and your risk of side effects will increase.

During pregnancy, this medication should be used only when clearly needed. Older adults may be more sensitive to the side effects of this drug, especially drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk flexeril for cramps of falling. Drowsiness, dizziness, dry mouth, constipation, or tiredness may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. You are encouraged to report negative side effects of prescription drugs to the FDA.

Related Disease Conditions

Store at room temperature away from light and moisture. This medication has been prescribed for your current condition only. Do not use it later for another condition unless your doctor directs you to do so. Alcohol or marijuana (cannabis) can make you more dizzy or drowsy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely.

Flexeril causes the muscles to relax by directing the brain and the spinal cord. Once digested, it usually starts working in approximately an hour, and for four to six hours, it will actively work on your muscles. If you are not able to swallow the extended-release capsule whole, mix the contents of the capsule with applesauce. Eat the mixture right away and swallow without chewing. After you eat the mixture, take a drink, and swish and swallow to make sure that you have received all the medication. Tell your care team if your symptoms do not start to get better or if they get worse.

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Because of limited comparable effectiveness data, choice of agent should be based on side-effect profile, patient preference, abuse potential, and possible drug interactions. For these reasons it is important for providers to employ safe and rational opioid prescribing practices when treating pregnant and postpartum patients. Opioid analgesics can be used for similar indications as in the non-pregnant patient, primarily for the treatment of moderate to severe pain when non-opioid therapies fail or are contraindicated. (Committee 2017) If an opioid analgesic is indicated, codeine should be avoided due to its link to cardiac and respiratory malformations. (Shaw 1992) Like prescribing in the non-pregnant patient, pregnant patients should have a risk assessment for prenatal substance abuse performed.

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Hence, using Flexeril while breastfeeding should be avoided unless doctors prescribe it after weighing the advantages and risks. Even if your doctor has recommended it, take the required precautions, such as not taking cyclobenzaprine with cold medications, not handling your infant after taking it, and so on. Alternatively, you can try various home treatments for muscle strains and pains. There are no adequate and well-controlled studies of AMRIX in pregnant women.

Data are conflicting but generally support the safety of NSAIDs in the first two trimesters; (Daniel 2014, Damase-Michel 2014) however recommendations and practice patterns are varied. We do not endorse the practice of routine pregnancy testing in women of childbearing age not known to be pregnant prior to the administration of NSAIDs. Cyclobenzaprine is a centrally acting skeletal muscle relaxant that is closely related to the tricyclic antidepressants (e.g., imipramine). The agent is not teratogenic or embryotoxic in mice, rats, and rabbits given doses up to 20 times the human dose (1).

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Pregnant women experience back strain and other pains, particularly in the later stages. Many practitioners recommend natural solutions for the same, which include a warm bath, low-heeled shoes or simply staying off the feet. Often, different sleeping positions such as placing pillows beneath the knees or the purchase of a body pillow, which may help to support the growing belly, also help with the pain.

Thus, if a mother needs Flexeril, she need not stop breastfeeding. However, it’s crucial to monitor the infant for drowsiness, proper weight gain, and developmental milestones to note any potential side effects (8). If you are a nursing mother, a thorough risk assessment of the drug before use is essential to ensure its safety and efficacy. Most drugs pass into breast milk, but they may or may not cause harm to your baby. People take muscle relaxants and expect to be able to function and work normally, including driving, operating machinery or doing cognitive tasks that require focus, which is a huge practical problem.

Nursing mothers must use cyclobenzaprine with caution. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.